Hassan Zaggi
The World Health Organisation (WHO) has christened the new variant of the COVID-19 virus that was recently discovered in South Africa as Omicron’.
The variant is said to be a Variant of Concern (VOC).
The WHO therefore, advised countries to enhance surveillance and sequencing efforts to better understand circulating SARS-CoV-2 variants; submit complete genome sequences and associated metadata to a publicly available database, such as GISAID; report initial cases/clusters associated with VOC infection to WHO through the IHR mechanism and where capacity exists and in coordination with the international community, perform field investigations and laboratory assessments to improve understanding of the potential impacts of the VOC on COVID-19 epidemiology, severity, effectiveness of public health and social measures, diagnostic methods, immune responses, antibody neutralization, or other relevant characteristics.
In a statement, the WHO said that: “Based on the evidence presented indicative of a detrimental change in COVID-19 epidemiology, the TAG-VE has advised WHO that this variant should be designated as a VOC, and the WHO has designated B.1.1.529 as a VOC, named Omicron.”
The global health body also called on individuals to take measures to reduce their risk of COVID-19, including proven public health and social measures such as wearing well-fitting masks, hand hygiene, physical distancing, improving ventilation of indoor spaces, avoiding crowded spaces, and getting vaccinated.
According to the Technical Advisory Group on SARS-CoV-2 Virus Evolution (TAG-VE), the B.1.1.529 variant was first reported to WHO from South Africa on 24 November 2021. The epidemiological situation in South Africa has been characterized by three distinct peaks in reported cases, the latest of which was predominantly the Delta variant.
In recent weeks, the WHO said, infections have increased steeply, coinciding with the detection of B.1.1.529 variant. “The first known confirmed B.1.1.529 infection was from a specimen collected on 9 November 2021.
“This variant has a large number of mutations, some of which are concerning. Preliminary evidence suggests an increased risk of reinfection with this variant, as compared to other VOCs.
“The number of cases of this variant appears to be increasing in almost all provinces in South Africa. Current SARS-CoV-2 PCR diagnostics continue to detect this variant. Several labs have indicated that for one widely used PCR test, one of the three target genes is not detected (called S gene dropout or S gene target failure) and this test can therefore be used as marker for this variant, pending sequencing confirmation.
“Using this approach, this variant has been detected at faster rates than previous surges in infection, suggesting that this variant may have a growth advantage.
”There are a number of studies underway and the TAG-VE will continue to evaluate this variant. WHO will communicate new findings with Member States and to the public as needed,” the statement said.
